GI Bleeding

David Green, MD, PhD

Northwestern University, Feinberg School of Medicine, Chicago, IL

This case was reviewed and updated in March 2010 by Dr. Alvin H. Schmaier and members of the Teaching Cases Subcommittee.

Copyright of the American Society of Hematology, 2006. ISSN: 1931-6860.

IV. DIFFERENTIAL DIAGNOSIS

This patient has a normal platelet count with a prolonged bleeding time, a normal PT, and a prolonged aPTT. Which of the following disorders is most likely?

Heparin therapy
Low factor VIII due to hemophilia A
Low factor IX due to hemophilia B
Low factor XI
Low factor XII, Low prekallikrein (PK) or high molecular weight kininogen (HK)
Lupus anticoagulant
von Willebrand’s disease

Have a question or comment about the ASH Teaching Cases? Please e-mail webmaster@hematology.org.