Anemia and Jaundice in a Newborn

Charles T. Quinn, MD, MS

Cincinnati Children's Hospital Medical Center

Copyright of the American Society of Hematology, 2006. ISSN: 1931-6860.

This case was reviewed and updated in June 2011 by The Teaching Cases Subcommittee.

IV. DIFFERENTIAL DIAGNOSIS

Which diagnostic possibilities for a hemolytic anemia should be considered in this neonate? Select the most likely possibilities.

Hemolytic disease of the newborn (HDN) due to Rh incompatibility
Maternal autoimmune hemolytic anemia
Hereditary Spherocytosis (HS)
Hemolytic disease of the newborn due to ABO incompatibility
Hemolytic disease of the newborn due to minor blood group incompatibility

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